Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0307124
PubChem CID
Molecular Formula
C6H14O
Molecular Weight
102.177 g/mol
Synonyms/Alias
[1-Hexanol; Hexan-1-ol; Hexyl alcohol; 111-27-3; HEXANOL; n-Hexanol; n-Hexyl alcohol; Amylcarbinol; 1-Hydroxyhexane; 1-Hexyl alcohol; Caproyl alcohol; Pentylcarbinol; Caproic alcohol; n-Hexan-1-ol; C6...
InChI Key
ZSIAUFGUXNUGDI-UHFFFAOYSA-N
InChI
InChI=1S/C6H14O/c1-2-3-4-5-6-7/h7H,2-6H2,1H3
IUPAC Name
hexan-1-ol
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

7 6 0 0 0 0 0 0 0 0999 V2000
-3.8971 -0.3214 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-2.5981 0.4286 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.2990 -0...

Experimental Data

Activity Data

Target Ion Channel
Potassium voltage-gated channel subfamily KQT member 1/E member 1 (minK)
Uniprot Accession Number
Function
Inhibitor
Species
Homo sapiens (Human)
IC50
IC50: 2700 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.4
Holding Potential
−30 mV mV
Temperature
22–25 °C
Test Method
Patch-clamping
Test Species
Xenopus laevis oocyte

Binding Information

Binding Site
Extracellular domain
Binding Site Residue
residue I257 at S4–S5 linker

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
7
Rotatable Bonds
4
logP
1.559
Complexity
31.2278
TPSA (Ų)
20.23
H-Bond Donors
1
H-Bond Acceptors
1
Ring Count
0
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